Low B-6 levels mean high levels of inflammation.

 

Vitamin B6 is involved in several metabolic processes such as,  amino acid, glucose, and lipid metabolism; production of neurotransmitters; histamine synthesis; synthesis of red blood cells; and gene expression.  We know that without enough B-6, a compound called homocysteine builds up in the body. Homocysteine damages blood vessel linings, setting the stage for plaque buildup when the body tries to heal the damage. 

Now there’s new evidence that low vitamin B-6 concentrations may be associated with inflammation, higher oxidative stress, and metabolic conditions in older adults. Data suggest that vitamin B-6 may influence cardiovascular disease risk through mechanisms other than homocysteine.

This study showed there was a strong dose-response relation of plasma vitamin B-6 concentration with plasma CRP (elevated levels of this protein mean inflammation and a potential for heart disease). Increasing B-6 levels were significantly associated with lower CRP concentrations. Metabolic syndrome, obesity, and diabetes were also significantly associated with low plasma B-6 concentrations.  

 

For information about CardioTone, our healthy-heart supplement that contains B vitamins, click here.

 

SOURCE

 Am J Clin Nutr 91: 337-342, 2010.